SBI – Department of Systems Biology and Bioinformatics
Faculty of Computer Science and Electrical Engineering
University of Rostock
Ulmenstrasse 69 | 18057 Rostock
Germany
+49 381 498-7571
olaf.wolkenhauer@uni-rostock.de
Projects
Research Projects
The AIR is to provide an interactive platform connecting scientific and medical communities.
Investigating the gut-brain-axis
The gut–brain axis (GBA) provides a bidirectional homeostatic communication between the gastrointestinal tract and the central nervous system. The interdisciplinary collaboration is going to fully explore a first comprehensive GBA cross-disease map of genetic, expression and regulatory changes associated with ulcerative colitis and schizophrenia disease entities.
RNA Sequencing (RNA-Seq) has become a widely used tool to study quantitative and qualitative aspects of the transcriptome. The variety of RNA-Seq protocols, experimental study designs and the characteristic properties of the organisms under investigation greatly affect downstream and comparative analyses. We provide easy access to comprehensive analysis of RNA-Seq experiments as a service. To do so, we leverage on the Galaxy framework, and organise dedicated workshops, training programs, and screencasts to make Life Scientists familiar with computational approaches to biological problems.
Academic background
| 2020 - present |
Research assistant |
| 2018 - 2020 |
M.Sc. in Medical Biotechnology |
| 2014 - 2018 |
B.Sc. in Medical Biotechnology |
Selected publications
The Atlas of Inflammation-Resolution (AIR)
A systems appraoch to investigate inflammation resolution by multicomponent medicinal product TR14
Workflow Development for the Functional Characterization of ncRNAs
Springer (2019), chapter in Computational Biology of Non-Coding RNA. Methods in Molecular Biology, vol 1912.
Machine-Learning-Assisted Construction of a Disease-Specific Molecular Interaction Network from Human Blood RNA-Seq Data
Master thesis within the study degree of Medical Biotechnology
Functional Characterization of Long Non-Coding RNAs from Stem Cell Derived Cardiomyocyte Cell Types
Bachelor thesis within the study degree of Medical Biotechnology