SBI – Department of Systems Biology and Bioinformatics
Faculty of Computer Science and Electrical Engineering
University of Rostock
Ulmenstrasse 69 | 18057 Rostock
Germany
+49 381 498-7571
olaf.wolkenhauer@uni-rostock.de

David Brauer

Projects

Research Projects

AIR: Atlas of Inflammation Resolution

The AIR is to provide an interactive platform connecting scientific and medical communities.

GB-XMap: Assessing the risk of gut-brain cross-diseases

Investigating the gut-brain-axis

The gut–brain axis (GBA) provides a bidirectional homeostatic communication between the gastrointestinal tract and the central nervous system. The interdisciplinary collaboration is going to fully explore a first comprehensive GBA cross-disease map of genetic, expression and regulatory changes associated with ulcerative colitis and schizophrenia disease entities.

de.STAIR: Structured Analysis and Integration of RNA-Seq Experiments

RNA Sequencing (RNA-Seq) has become a widely used tool to study quantitative and qualitative aspects of the transcriptome. The variety of RNA-Seq protocols, experimental study designs and the characteristic properties of the organisms under investigation greatly affect downstream and comparative analyses. We provide easy access to comprehensive analysis of RNA-Seq experiments as a service. To do so, we leverage on the Galaxy framework, and organise dedicated workshops, training programs, and screencasts to make Life Scientists familiar with computational approaches to biological problems.

2020 - present	Research assistant Department of Systems Biology and Bioinformatics University of Rostock Rostock, Germany
2018 - 2020	M.Sc. in Medical Biotechnology University of Rostock Rostock, Germany
2014 - 2018	B.Sc. in Medical Biotechnology University of Rostock Rostock, Germany

Selected publications

Fibroblast Growth Factor 21 as a Potential Biomarker for Improved Locomotion and Olfaction Detection Ability after Weight Reduction in Obese Mice

Power Guerra N, Parveen A, Bühler D, Brauer DL, Müller L, Pilz K, Witt M, Glass Ä, Bajorat R, Janowitz D, Wolkenhauer O, Vollmar B, Kuhla A

Nutrients 2021

DOI: https://doi.org/10.3390/nu13092916

URL: https://www.mdpi.com/2072-6643/13/9/2916/htm

The Atlas of Inflammation-Resolution (AIR)

Serhan CN, Gupta SK, ... , Smita S, Schopohl P, Hoch M, Gjorgevikj D, Khan FM, Brauer D, ... , Wolkenhauer O

Molecular Aspects of Medicine 2020

DOI: https://doi.org/10.1016/j.mam.2020.100894

Pubmed: https://pubmed.ncbi.nlm.nih.gov/32893032/

URL: https://www.sciencedirect.com/science/article/pii/S0098299720300960

A systems appraoch to investigate inflammation resolution by multicomponent medicinal product TR14

Schopohl P, Smita S, Khan F, Gebhardt T, Hoch M, Brauer D, Cesnulevicius D, Schultz M, Wolkenhauer O, Gupta S

Annals of the Rheumatic Diseases 2019;78:1496.

DOI: http://dx.doi.org/10.1136/annrheumdis-2019-eular.5084

URL: https://ard.bmj.com/content/annrheumdis/78/Suppl_2/1496.1.full.pdf

Workflow Development for the Functional Characterization of ncRNAs

Wolfien M, Brauer DL, Bagnacani A, Wolkenhauer O

Springer (2019), chapter in Computational Biology of Non-Coding RNA. Methods in Molecular Biology, vol 1912.

DOI: https://doi.org/10.1007/978-1-4939-8982-9_5

Machine-Learning-Assisted Construction of a Disease-Specific Molecular Interaction Network from Human Blood RNA-Seq Data

Brauer DL

Master thesis within the study degree of Medical Biotechnology

Functional Characterization of Long Non-Coding RNAs from Stem Cell Derived Cardiomyocyte Cell Types

Brauer DL

Bachelor thesis within the study degree of Medical Biotechnology

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David Brauer

Projects

Academic background

Selected publications