Dept. of Systems Biology and Bioinformatics is a part of the University of Rostock, Germany Universität Rostock

Sherry Freiesleben

Image: Sherry Freiesleben

Current Projects

Complex DNA lesions and their impact on cellular radiation response (Collar)
The investigations will deepen our knowledge on the impact of radiation-induced complex DNA lesions with spinoffs for radiation protection and the development of new, advanced tumor therapy strategies.

Research Interest

microRNAs and data integration -  Why should we even bother?

microRNAs (miRNAs) are non-coding RNAs that post-transcriptionally regulate gene expression. They partake in diverse biological processes and have been reported to be involved in many diseases. Their expression profiles can easily be investigated since they are present in a stable form in human blood and plasma.

Therefore, what role do these tiny molecules play in the development of diseases?

To answer this question, I first analyze transcriptomics data in order to identify candidate miRNAs and genes. I then make use of data originating from various databases and of data integration methods to generate regulatory networks. After constructing these networks, I apply network analysis methods such as to uncover regulatory interactions involving miRNAs which may help us better understand the role of these molecules in diseases.

Academic Background

2011 - present
PhD: Medical Bioinformatics
University of Rostock, Rostock, Germany

2009 - 2011
Master of Science: Medical Biotechnology
University of Rostock, Rostock, Germany

2009 - 2006
Bachelor of Science: Major Physiology, Minor Physics
McGill University, Montreal, Canada

Summer Semester 2006
Guest Student: Physics
University of Rostock, Rostock, Germany

2003 - 2005
Diploma of College Studies: Health Science
Vanier College, Montreal, Canada

Contact Details

Systems Biology and Bioinformatics
Ulmenstrasse 69 (building 3, 3rd floor)
18057 Rostock, Germany
Room 415a

Phone: +49 381 498-7579
Fax: +49 381 498-7572
Email: sherry.freiesleben(at)