SBI – Department of Systems Biology and Bioinformatics
Faculty of Computer Science and Electrical Engineering
University of Rostock
Ulmenstrasse 69 | 18057 Rostock
+49 381 498-7571
"I am interested in multi-omics data integration and analysis and my research activities include biological data analysis and interpretation, molecular docking and molecular dynamics simulations along with statistical analysis."
Currently I am working on HICE (Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health) project where multiomics data is being generated from the lung cells exposed to various aerosols from ship diesel and wood combustion. Detail chemometric data is also being generated from the exposure aerosol.
I am specifically working on the biological targets of various chemical entities present in the aerosols. The work involves development of computational methodologies to integrate chemometirc aerosol data with multi-omics exposure data for predicting potential biomarkers for health effects cause by aerosols.
The AIR is to provide an interactive platform connecting scientific and medical communities.
|2008 - 2012||Ph.D. (Bioinformatics)
Thesis title: "Identification of suitable target for GsMTx-4, a Venom peptide from Tarantula for the treatment of High Blood Pressure"
|2003 - 2005||
M. Sc. (Bioinformatics)
|2000 - 2003||
B.Sc. (Chemistry, Botany, Zoology)
|1997 - 2000||
|1995 - 1997||
High School (Science)
A systems appraoch to investigate inflammation resolution by multicomponent medicinal product TR14
Schopohl P, Smita S, Khan F, Gebhardt T, Hoch M, Brauer D, Cesnulevicius D, Schultz M, Wolkenhauer O, Gupta S
Deciphering hallmark processes of aging from interaction networks
Smita S, Lange F, Wolkenhauer O, Köhling R
Biochim Biophys Acta. 2016; S0304-4165(16)30264-1.
Computational analysis and modeling the effectiveness of "Zanamivir" targeting neuraminidase protein in pandemic H1N1 strains
Gupta SK, Gupta SK, Smita S, Srivastava M, Lai X, Schmitz U, Rahman Q, Wolkenhauer O, Vera J (2011)
Infection, Genetics and Evolution 11: 1072 - 1082
Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase
Gupta SK, Srivastava M, Akhoon BA, Smita S, Schmitz U, Wolkenhauer O, Vera J, Gupta SK (2011)
Infection, Genetics and Evolution 11: 308 - 319
Geraniol and limonene interaction with 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase for their role as cancer chemo-preventive agents
Pattanayak M, Seth PK, Smita S, Gupta SK (2009)
Journal of Proteomics & Bioinformatics 2: 466-474
Enriching biotechnology with recent bioinformatics tools and protocols
Gupta SK, Smita S, Rahman Q
in: Recent trends in Biotechnology; Singh MP, Agrawal A, Sharma B (eds.); Nova Science Publishers Inc. 2011.
ISBN 13 (print): 9781608761487
Education and Work Experience
- Wissenschaftliche Mitarbeiterin in Comprehensive Molecular Analytics, Helmholtz Zentrum München
- Post-doctoral Fellow Oscar Langendorff Institute für Physiologie der Universitätsmedizin, Rostock
- Post-doctoral Fellow at Department of Systems Biology and Bioinformatics, Rostock, Germany